Prevention of Age-Related Macular Degeneration

             Prevention of Age-Related Macular Degeneration

Association of Genetic Polymorphisms and Age-related Macular Degeneration in Chinese population.

Association of Genetic Polymorphisms and Age-related Macular Degeneration in Chinese population.

Multicenter case-control study. 535 AMD patients and 469 controls were recruited from 16 centers...11 single nucleotide polymorphisms (SNPs) in complement H (CFH), 2 in age-related maculopathy susceptibility 2 (ARMS2) and 2 in high-temperature requirement factor A1 (HTRA1) were noted to be significantly associated with AMD....Gene variants in CFH, ARMS2 and HTRA1 contribute to AMD in Chinese population.

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